This paper aims to explore the new connotation, constituent elements, and systematic cultivation paths of college teachers’ literacy in the digital-intelligent era. Firstly, it analyzes the macro background of education reform driven by technologies such as artificial intelligence and big data, and then sorts out the focus and gaps of current research through literature review. Based on theories such as the Iceberg Model, this paper constructs a teacher’s digital-intelligent competence model covering implicit literacy and explicit abilities. Corresponding to this model, the paper proposes collaborative cultivation strategies from multiple dimensions including internal drive stimulation, external drive support, role transformation, and systematic construction. Finally, the future research directions and practical deepening are prospected, aiming to provide a reference for the construction of college teachers’ teams and the high-quality development of education.