With the emergence of the concept of low-altitude economy and the continuous upgrading of avionics technology, cultivating aerospace professionals with single-chip microcomputer (SCM) knowledge and practical abilities has become an important reform direction for undergraduate education. From the perspective of course application, this paper explores the necessity of introducing SCM courses and reforming teaching methods for aerospace majors at the undergraduate level, and puts forward reform suggestions in teaching content, teaching methods, practical links, and evaluation systems. It aims to build a curriculum system that not only conforms to the characteristics of aerospace majors but also strengthens students’ SCM engineering application literacy and cultivates applied compound talents for the aviation industry related to the low-altitude economy.