In the modern higher education music curriculum system, the teacher-student interaction mode is a key factor affecting the effectiveness of piano teaching. However, the current teacher-student interaction mode in piano teaching still has limitations, such as one-way transmission and a lack of personalized feedback. Based on constructivist learning theory and social interaction theory, combined with information technology, this paper explores the optimization strategy of interaction mode in the piano teaching process of normal universities. This study adopts classroom observation and interview methods to analyze the impact of different interaction modes on students’ piano learning effectiveness, learning engagement, and autonomous learning ability. The research results show that the constructivist interactive teaching mode supported by information technology can significantly enhance students’ interest in learning and playing skills, optimize the classroom teaching atmosphere, and promote the improvement of their comprehensive literacy.