In the context of globalization and rapid development of information technology, the transformation of industrial structure has become a major force driving China’s economic and social development. Under this situation, as an important component of China’s higher vocational education, the information construction of the business and trade professional group is of great significance. The construction of informatization can not only improve the education quality of the business and trade professional group, but also closely connect with the needs of the industry, providing strong talent support for the transformation and upgrading of the industry. Aiming at the problems existing in China’s current economic and social development, this paper proposes a new economic and trade professional system based on information technology, and puts forward corresponding solutions.