With the rapid development of the intelligent manufacturing industry, the demand for technical talents in industrial robot technology has become increasingly urgent. Focusing on the application value of virtual simulation technology in the practical teaching of industrial robot major and combining with the national vocational education reform policies, this paper explores the innovative role of virtual simulation technology in the practical teaching model from four dimensions: teaching cost optimization, safety improvement, scenario expansion, and evaluation innovation. The research shows that virtual simulation technology can effectively solve the “three highs and three difficulties” problems in traditional practical teaching, promote the in-depth development of the integration of industry and education, and provide strong support for cultivating high-quality technical and skilled talent in the field of industrial robots.