Resource recycling science and engineering is a new interdisciplinary subject. In order to meet the needs of the development of the circular economy, it is highly necessary to improve students’ innovative abilities and practical skills. This paper analyzes the problems existing in the practical teaching of this major and puts forward some approaches to the construction of practical teaching of resource-based major from the aspects of content system construction of practical teaching of resource recycling major, deep cooperation between schools and enterprises, construction of dual-teacher teams, and integration teaching of industry-university-research competition. It has effectively improved the training quality of applied talents in the resource recycling major.