This paper explores the impact of student club development on the scientific literacy of vocational college students. As society increasingly values innovation and scientific literacy, vocational colleges bear a significant responsibility in cultivating students’ overall quality. Taking the Modeling and Simulation student club as a case study, the research team conducted a 12-week study. The results indicate that various club activities aimed at enhancing scientific literacy have positively influenced the development of students’ scientific competencies. Students’ practical skills and innovative thinking have been effectively improved. Our research demonstrates the positive role of student clubs in enhancing the scientific literacy of vocational college students, providing valuable experience and references for the development of similar clubs in the future.