Against the backdrop of the rapid penetration of Artificial Intelligence Generated Content (AIGC) into higher education, teacher-student relationships in private universities are undergoing profound transformations. Based on Foucault’s theory of knowledge and power, this paper takes private universities as a specific research field, focuses on the interactive dimension between teachers, students and AIGC technology, explores the two-way logic of knowledge-power between teachers and students as well as between human subjects and technology with the intervention of AIGC, and analyzes practical dilemmas including power imbalance, communication alienation and excessive technological discipline arising in the process of AIGC empowering teacher-student relationships in private universities.