Based on the core requirements of the strategy of building a powerful education nation for higher education, namely “self-improvement and excellence, digital and intelligent empowerment, and open integration,” this paper starts from the functional positioning of college administrative organs, analyzes the mission and tasks under the new situation, and explores the adaptability of knowledge management theory to the practice of college administration. It constructs a knowledge management model from the dual dimensions of intangible assets and digital assets, designs the system framework, and refines the functional scheme of the digital and intelligent knowledge management platform, and puts forward construction suggestions, providing a practical path for supporting the construction of a powerful education nation.