The establishment of a modernized university teaching management operation mechanism is an important element of the comprehensive reform of higher education. University teaching management is characterized by the weakening of academic power, the expansion of administrative power, and the lack of clarity in the responsibilities and powers of universities and colleges. To realize the modernization of the governance system and governance capacity of higher education, it is necessary to reconstruct the internal power structure and power operation mechanism of university teaching management, to make the teaching management organization shift to flattening, the power of the university ministry to the power of the faculties and departments vertically downward, and to form a governance mechanism of division of labor and collaboration between academic power and administrative power. A case study on the reform of the operation mechanism of teaching management was shared, which illustrated a teaching management model applied in University G. Through the Undergraduate “Faculty Committee,” “Teaching Working Committee” and the “Teaching Steering Committee,” a teaching management operation mechanism integrating the separation of powers of “legislative power, administrative power and supervisory power” was gradually constructed, and the implementation effect was good.