The innovative spirit in traditional Chinese culture is the result of 5000 years of civilization. It is built upon theinnovative thinking and values of Confucianism, Taoism, Legalism, Mohism, and other schools of thought. These values have guided and propelled the development of modern science and technology. The spirit of studying diligently andseeking truth from facts from the Confucian culture has stimulated the learning and innovative skills of modern scientificand technological talents. Taoist’s idea of conforming to nature and governing according to the flow has provided newideas and methods for scientific and technological innovation. The legal spirit of Legalism has provided a strong institutional guarantee for the development of science and technology. The spirit of universal love, non-aggression, and unityand cooperation in Mohism has stimulated the vitality of scientific and technological innovation. These innovative spiritshave not only provided ideological guidance and institutional guarantees for the development of science and technologybut also driven the development of modern science and technology. In the new era, we should inherit and carry forward theinnovative spirit of the traditional Chinese culture to ensure the continuous development of modern science and technologyand help realize the great rejuvenation of the Chinese nation.