With the increasing frequency of global medical exchanges, the English translation of clinical medicine disease names has become a key factor affecting medical safety, the quality of academic exchanges, and the level of medical education. Meanwhile, there are certain problems in the English translation of clinical medicine disease names in China currently, mainly manifested in the prevalence of multiple translations for one term, prominent issues of literal translation and mistranslation, and inconsistent naming principles. Based on this, this paper focuses on the strategies for standardized English translation of clinical medicine disease names. By explaining the root causes of the problems existing in the current translation field, it further puts forward standardized suggestions from aspects such as establishing authoritative reference standards, following the basic principles of “respecting the originator, following conventions, and adhering to scientific norms”, strengthening medical English education, and using modern tools to assist learning. These efforts aim to gradually unify and standardize disease names, reduce ambiguities and errors, and lay a foundation for international medical exchanges and evidence-based medical research.