ARTICLE
31 August 2026

Clinical Research and Integrated Management of Post-surgical Gastroparesis after Colon Cancer Resection

Juyi Li1 Lihong Ka1 Jingwen Chen2 Xiang Wang3 Xin Wei1 Pengfei Hu4*
Show Less
1 Nursing College of Gansu Medical College, Pingliang 744000, Gansu, China
2 Public Health, Gansu Medical College, Pingliang 744000, Gansu, China
3 Clinical Medicine of Gansu Medical College, Pingliang 744000, Gansu, China
4 Mi Huangfu College of Gansu Medical College, Pingliang 744000, Gansu, China
JCNR 2026 , 10(8), 332–335; https://doi.org/10.26689/JCNR.v10i8.15427
© 2026 by the Author. Licensee: Bio-Byword Scientific Publishing Pty Ltd, Australia. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

Postsurgical gastroparesis syndrome (PGS) is a gastric motility disorder with non-mechanical gastric outlet obstruction that occurs following colon cancer resection. Although its incidence is said to be less than that of post-upper abdominal surgeries, its onset may cause a significant delay in postoperative progress and prolong hospitalization, and could also potentially delay the initiation of adjuvant chemotherapy. In this review, we present a systematic overview of the etiological mechanisms, diagnostic modalities, possible prevention, and a comprehensive Therapeutic approach for PGS in the context of colon cancer, putting a special emphasis on the possible detrimental impact of lymphadenectomy on the perigastric neural innervation and vascular supply in right-sided colon cancer procedures. We endeavor to provide practical references for the early clinical recognition and the standardized management of this challenging complication.

Keywords
Gastroparesis syndrome
Colon cancer
Integrated therapeutic strategy
Postoperative complications
References

[1]       Qian Z, Wu D, Zhu C, et al., 2026, Case Report: Case of Wernicke's Encephalopathy Complicated by Postoperative Gastroparesis Following Sigmoid Colon Malignant Tumor Surgery with a Literature Review. Frontiers in Oncology, 16: 1715017.

[2]       Grüter A, Vlug M, Spaanderman I, et al., 2024, Challenging Case of Deficient Mismatch Repair Right-Sided Locally Advanced Adenocarcinoma of the Ascending Colon with Duodenal Involvement: A Case Report Including Step-by-Step Video of Operation. International Journal of Surgery Case Reports, 114: 109137.

[3]       Wang G, Pan S, 2025, Factor Analysis of Postsurgical Gastroparesis Syndrome After Right Hemicolectomy for Colon Cancer. Oncology Letters, 29(3): 154.

[4]       Stormark K, Krarup P, Sjövall A, et al., 2020, Anastomotic Leak After Surgery for Colon Cancer and Effect on Long-Term Survival. Colorectal Disease, 22(9): 1108–1118.

[5]       Yde J, Larsen H, Laurberg S, et al., 2018, Chronic Diarrhea Following Surgery for Colon Cancer-Frequency, Causes and Treatment Options. International Journal of Colorectal Disease, 33(6): 683–694.

[6]       Lundqvist E, Westberg K, Boman S, et al., 2025, Outcome After Surgery for Colon Cancer in a National Cohort of Patients with and Without Inflammatory Bowel Disease. Alimentary Pharmacology & Therapeutics, 62(11–12): 1181–1191.

[7]       Guraya S, 2019, Pattern, Stage, and Time of Recurrent Colorectal Cancer After Curative Surgery. Clinical Colorectal Cancer, 18(2): e223–e228.

[8]       Lin Y, Cheng H, Huang S, et al., 2022, Comparison of Two-Stage and Three-Stage Surgery for Obstructing Left-Sided Colon Cancer. ANZ Journal of Surgery, 92(6): 1466–1471.

[9]       Ketelaers S, Fahim M, Rutten H, et al., 2020, When and How Should Surgery Be Performed in Senior Colorectal Cancer Patients? European Journal of Surgical Oncology, 46(3): 326–332.

[10]     Scheepers E, Vink G, Schiphorst A, et al., 2023, Health-Related Quality-of-Life Trajectories During/After Surgery and Adjuvant Chemotherapy in Patients with Colon Cancer. European Geriatric Medicine, 14(3): 565–572.

[11]     Sier M, Gielen A, Tweed T, et al., 2024, Accelerated Enhanced Recovery After Colon Cancer Surgery with Discharge Within One Day After Surgery: A Systematic Review. BMC Cancer, 24(1): 102.

[12]     Biondo S, Gálvez A, Ramírez E, et al., 2019, Emergency Surgery for Obstructing and Perforated Colon Cancer: Patterns of Recurrence and Prognostic Factors. Techniques in Coloproctology, 23(12): 1141–1161.

[13]     Khan M, Cahill R, 2021, Peroperative Personalized Decision Support and Analytics for Colon Cancer Surgery: Short Report. European Journal of Surgical Oncology, 47(2): 477–479.

[14]     Chi P, Huang S, 2022, Delayed Gastric Emptying After Surgery for Transverse Colon Cancer: Diagnosis, Management and Prevention. Chinese Journal of Gastrointestinal Surgery, 25(6): 493–499.

[15]     Jiménez I, Pacha M, Pares D, et al., 2019, Survival and Quality of Life After Surgery for Colorectal Cancer in the Elderly: A Comparative Study. Revista Española de Enfermedades Digestivas, 111(3): 193–198.

Share
Back to top