Volume 10,Issue 8
Bibliometric Analysis on the Integrated Chinese and Western Medicine Treatment of Alcohol Poisoning
Objective: To systematically analyze the research status, hot topics, and knowledge structure in the field of integrated Chinese and Western medicine for alcohol poisoning based on bibliometric methods, reveal the development context and integration trend of this field, and provide a reference basis for subsequent research. Methods: Relevant literature on integrated Chinese and Western medicine treatment of alcohol poisoning was retrieved from Chinese databases including CNKI, Wanfang, VIP, and international databases such as PubMed and Web of Science. The Sentence-BERT model was adopted for semantic vector encoding, combined with UMAP dimensionality reduction and HDBSCAN density clustering analysis. The c-TF-IDF algorithm was used to extract topic keywords, and topic similarity heat maps, document scatter plots, and hierarchical clustering dendrograms were constructed. Results: A total of 8 core research topics were identified. Western medicine emergency and clinical treatment systems (Topic 0–3) accounted for the mainstream of the literature, focusing on “treating symptoms” and clinical pathway management of acute poisoning. Studies on traditional Chinese medicine (TCM) and experimental pharmacology (Topic 4–5) focused on mechanism exploration and TCM intervention. Neural mechanism and rehabilitation management (Topic 6–7) paid attention to the deep-seated mechanism and long-term prognosis of diseases, which are currently weak research links. Semantic spatial analysis showed that there was an obvious “semantic gap” between the Western medicine emergency system and TCM traditional therapies, and a tight knowledge integration network had not been formed between the two. Conclusion: The current research on integrated Chinese and Western medicine for alcohol poisoning presents a pattern of “Western medicine dominating and TCM marginalized”. There are problems such as disconnection between laboratory research and clinical practice, and insufficient connection between acute treatment and long-term rehabilitation. In the future, efforts should be made to build a full-cycle management model of “treating both symptoms and root causes”, promote the clinical transformation of TCM pharmacological achievements, and reshape a three-dimensional diagnosis and treatment path including “TCM syndrome differentiation classification–Western medicine symptomatic support–TCM rehabilitation follow-up”.
[1] Expert Group for Consensus on Diagnosis and Treatment of Acute Alcohol Poisoning, 2014, Consensus on Diagnosis and Treatment of Acute Alcohol Poisoning. Chinese Journal of Emergency Medicine, 23(2): 135–138.
[2] World Health Organization, 2018, Harmful Use of Alcohol Kills More Than 3 Million People Each Year, Most of Them.
[3] Lai D, 2022, Efficacy of Naloxone in Emergency Treatment of Severe Acute Alcohol Poisoning. Journal of Rational Clinical Medication, 15(29): 100–102.
[4] Zhang Z, 2005, Synopsis of Prescriptions of the Golden Chamber. People’s Medical Publishing House, Beijing.
[5] Li D, 2006, Treatise on the Spleen and Stomach. People’s Medical Publishing House, Beijing.
[6] Gao M, Zhang X, Luo D, et al., 2023, Anti-Intoxication Effect and Mechanism of Jingfang Granule on Drunken Mice Model. Chinese Herbal Medicines, 54(4): 1164–1172.
[7] Chen N, Chen D, Zhang L, et al., 2014, Clinical Observation on 40 Cases of Severe Acute Alcohol Poisoning Treated with Integrated Chinese and Western Medicine. Hebei Journal of Traditional Chinese Medicine, 36(7): 1036–1037.
[8] Ding Y, Zuo F, Li C, 2021, Effects of Xingnaojing Injection Combined with Naloxone on Oxygen Metabolism Indexes and Oxidative Stress Response in Patients with Acute Alcohol Poisoning. Modern Diagnosis & Treatment, 32(23): 3734–3735.
[9] Liu Y, Guo Y, 2020, Clinical Observation of Naloxone Combined with Xingnaojing in Treating Acute Alcohol Poisoning Complicated with Arrhythmia. Hebei Medical Journal, 26(5): 872–876.
[10] Li H, He Q, 2024, Clinical Efficacy Analysis of Compound Danshen Injection Combined with Naloxone in Emergency Treatment of Ethanol Poisoning. Electronic Journal of Modern Medicine and Health Research, 8(2): 69–71.
[11] He S, Liang Z, Huang S, 2022, Analysis of Clinical Effect of Integrated Chinese and Western Medicine in Treating Acute Alcohol Poisoning. Chinese and Foreign Medical Research,
[12] Li P, 2021, Discussion on Integrated Chinese and Western Nursing and Implementation Effect of Acute Alcohol Poisoning. Chinese Medical Guide, 19(36): 192–193.
[13] Li J, Chen C, 2016, CiteSpace: Text Mining and Visualization of Scientific and Technological Literature. Capital University of Economics and Business Press, Beijing.
[14] Li X, Liang Y, Li X, 2023, Efficacy Analysis of Naloxone Injection in Patients with Acute Alcohol Poisoning. Shenzhen Journal of Integrated Traditional Chinese and Western Medicine, 33(9): 20–23.
[15] Liu X, Wang S, Li P, 2025, Observation on the Efficacy of Xingnaojing Combined with Naloxone in Treating Acute Alcohol Poisoning. Shenzhen Journal of Integrated Traditional Chinese and Western Medicine, 2025(8): 93–95 + 99.
