Aiming at the disconnection between clinical practical ability and long-term career development literacy in the postgraduate education of Zhuang Medicine, this study deeply explores the transformation mechanism and innovative cultivation between the two. Firstly, this study constructs a three-level analytical framework of “individual–knowledge–environment”, and clarifies that the transformation is a socialized process synergistically promoted by the internal drive of cultural identity, knowledge creation through the integration of clinical practice and scientific research, as well as empowerment by diverse communities of practice and “dual-competent” supervisors. Furthermore, this study proposes a systematic solution of “One Core, Two Wings, Three Synergies” guided by the cultivation of “scholarly Zhuang Medicine physicians.” By building a practical platform integrating clinical practice, scientific research and community service, constructing a dual-module curriculum system of cultural inheritance and career development, and deepening the collaborative education ecosystem among master-apprenticeship and academic education, clinical practice and community service, as well as multiple disciplines, this solution aims to achieve a fundamental transition of postgraduates from “skill inheritors” to “innovative pioneers adhering to the right principles.” This study provides a reform blueprint with both theoretical depth and practical feasibility for the cultivation of high-level and interdisciplinary talents in Zhuang Medicine and other ethnic medicines.