ARTICLE
26 July 2026

AI-Assisted Oral Imaging Diagnosis in Clinical Applications of Dentistry: A Review

Siping Zheng1
Show Less
1 School of Dentistry, Lincoln University College, Petaling Jaya 47301, Selangor, Malaysia
APM 2026 , 11(7), 91–97; https://doi.org/10.26689/APM.v11i7.15571
© 2026 by the Author. Licensee: Bio-Byword Scientific Publishing Pty Ltd, Australia. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

Artificial intelligence (AI), particularly deep learning and convolutional neural networks (CNNs), is increasingly used in dental and maxillofacial imaging for classification, detection, segmentation, and quantitative assessment. Applications include dental caries, periodontal bone loss, jaw lesions, orthodontic measurements, and impacted-tooth localization. This narrative review emphasizes the technical foundations of AI-assisted oral imaging, including CNN architectures, preprocessing, annotation, augmentation, evaluation, and external validation, while summarizing representative clinical applications. Current studies report promising performance in selected tasks, but generalizability is constrained by heterogeneous datasets, imaging protocols, annotation standards, and limited multicenter validation. Clinical translation further requires explainability, workflow integration, regulatory oversight, and prospective evaluation.

Keywords
Artificial intelligence
Oral imaging
Diagnosis
Deep learning
Dental caries
Periodontal disease
CBCT
References

[1] Miki Y, Muramatsu C, Hayashi T, et al., 2017, Classification of Teeth in Cone-Beam CT Using Deep Convolutional Neural Network. Computers in Biology and Medicine, 80: 24–29.

[2] Poedjiastoeti W, Suebnukarn S, 2018, Application of Convolutional Neural Network in the Diagnosis of Jaw Tumors. Healthcare Informatics Research, 24(3): 236–241.

[3] Kim J, Lee H, Song I, et al., 2019, DeNTNet: Deep Neural Transfer Network for the Detection of Periodontal Bone Loss Using Panoramic Dental Radiographs. Scientific Reports, 9(1): 17615.

[4] Orhan K, Bilgir E, Bayrakdar I, et al., 2021, Evaluation of Artificial Intelligence for Detecting Impacted Third Molars on Cone-Beam Computed Tomography Scans. Journal of Stomatology, Oral and Maxillofacial Surgery, 122(4): 333–337.

[5] Başaran M, Çelik Ö, Bayrakdar I, et al., 2022, Diagnostic Charting of Panoramic Radiography Using Deep-Learning Artificial Intelligence System. Oral Radiology, 38(3): 363–369.

[6] Ardila C, Vivares-Builes A, Pineda-Vélez E, 2026, From Algorithmic Performance to Clinical Translation: Translational Readiness of Imaging-Based Artificial Intelligence in Dentistry—A Systematic Review. Healthcare, 14(13): 1952.

[7] Engels P, Meyer O, Schönewolf J, et al., 2022, Automated Detection of Posterior Restorations in Permanent Teeth Using Artificial Intelligence on Intraoral Photographs. Journal of Dentistry, 121: 104124.

[8] Schlickenrieder A, Meyer O, Schönewolf J, et al., 2021, Automatized Detection and Categorization of Fissure Sealants From Intraoral Digital Photographs Using Artificial Intelligence. Diagnostics, 11(9): 1608.

[9] Nomura Y, Xu Q, Shirato H, et al., 2019, Projection-Domain Scatter Correction for Cone Beam Computed Tomography Using a Residual Convolutional Neural Network. Medical Physics, 46(7): 3142–3155.

[10] Alajaji S, Amarin R, Masri R, et al., 2024, Detection of Extracranial and Intracranial Calcified Carotid Artery Atheromas in Cone Beam Computed Tomography Using a Deep Learning Convolutional Neural Network Image Segmentation Approach. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 138(1): 162–172.

[11] Lee J, Kim D, Jeong S, et al., 2018, Detection and Diagnosis of Dental Caries Using a Deep Learning-Based Convolutional Neural Network Algorithm. Journal of Dentistry, 77: 106–111.

[12] Pul U, Tichy A, Pitchika V, et al., 2025, Impact of Artificial Intelligence Assistance on Diagnosing Periapical Radiolucencies: A Randomized Controlled Trial. Journal of Dentistry, 160: 105868.

[13] Görürgöz C, Orhan K, Bayrakdar I, et al., 2022, Performance of a Convolutional Neural Network Algorithm for Tooth Detection and Numbering on Periapical Radiographs. Dentomaxillofacial Radiology, 51(3): 20210246.

[14] Albano D, Galiano V, Basile M, et al., 2024, Artificial Intelligence for Radiographic Imaging Detection of Caries Lesions: A Systematic Review. BMC Oral Health, 24(1): 274.

[15] Naeimi S, Darvish S, Salman B, et al., 2024, Artificial Intelligence in Adult and Pediatric Dentistry: A Narrative Review. Bioengineering, 11(5): 431.

[16] Kühnisch J, Meyer O, Hesenius M, et al., 2022, Caries Detection on Intraoral Images Using Artificial Intelligence. Journal of Dental Research, 101(2): 158–165.

[17] Sukegawa S, Ono S, Tanaka F, et al., 2023, Effectiveness of Deep Learning Classifiers in Histopathological Diagnosis of Oral Squamous Cell Carcinoma by Pathologists. Scientific Reports, 13(1): 11676.

[18] Zhu J, Chen Z, Zhao J, et al., 2023, Artificial Intelligence in the Diagnosis of Dental Diseases on Panoramic Radiographs: A Preliminary Study. BMC Oral Health, 23(1): 358.

[19] Roy R, Chopra A, Karmakar S, et al., 2025, Applications of Artificial Intelligence (AI) for Diagnosis of Periodontal/Peri-Implant Diseases: A Narrative Review. Journal of Oral Rehabilitation, 52(8): 1193–1219.

[20] Giraldo-Roldán D, Nakamura T, Claret A, et al., 2026, Impact of Transfer Learning on Convolutional Neural Networks for Odontogenic Tumor Diagnosis. Head and Neck Pathology, 20(1): 24.

[21] Kamat M, Datar U, Kumar V, 2025, Insights Into AI-Enabled Early Diagnosis of Oral Cancer: A Scoping Review. Cureus, 17(7): e88407.

[22] Makaremi M, Sadr A, Marcy B, et al., 2023, An Interpretable Machine Learning Approach to Study the Relationship Between Retrognathia and Skull Anatomy. Scientific Reports, 13(1): 18130.

[23] Mureșanu S, Almășan O, Hedeșiu M, et al., 2023, Artificial Intelligence Models for Clinical Usage in Dentistry with a Focus on Dentomaxillofacial CBCT: A Systematic Review. Oral Radiology, 39(1): 18–40.

[24] Alahmari M, Alahmari M, Almuaddi A, et al., 2025, Accuracy of Artificial Intelligence-Based Segmentation in Maxillofacial Structures: A Systematic Review. BMC Oral Health, 25(1): 350.

[25] Ahmed N, Abbasi M, Zuberi F, et al., 2021, Artificial Intelligence Techniques: Analysis, Application, and Outcome in Dentistry—A Systematic Review. BioMed Research International, 2021: 9751564.

[26] Chen R, Lee Y, Li J, 2026, The Science Behind Machine Learning, Deep Learning, and Active Learning. Dental Clinics of North America, 70(2): 351–359.

[27] Syed A, Ozen D, Duman S, et al., 2026, Radiographic Data Segmentation as a Tool in Machine Learning and Deep Learning Artificial Intelligence Algorithms. Dental Clinics of North America, 70(2): 331–349.

[28] Mathur A, Mehta V, Bhadania M, et al., 2026, Artificial Intelligence in Dental Implant Identifications, Planning Accuracies, and Success Predictions: An Umbrella Review. The Journal of Prosthetic Dentistry, 136(2): 412–421.

Share
Back to top