Keywords
Atorvastatin calcium tablets
Hypertension
Coronary heart disease
Submitted : 2025-08-13
Accepted : 2025-08-28
Published : 2025-09-12
Abstract
Hypertension combined with coronary heart disease, as a common chronic disease, often coexists, which has a significant impact on patients’ health and quality of life. As a compound preparation, amlodipine and atorvastatin calcium tablets have shown significant efficacy in the treatment of hypertension combined with coronary heart disease in recent years. This study systematically analyzes the pharmacological characteristics, clinical treatment effect, and safety of amlodipine and atorvastatin calcium tablets. The research points out that this compound preparation can significantly regulate blood pressure, optimize myocardial blood supply, and thus effectively reduce the occurrence of adverse cardiovascular events.
References
Shi XL, Zhao GY, Liu JM, 2021, Effects of Amlodipine and Atorvastatin on Cardiovascular Active Peptides, Inflammatory Factors, and Vascular Endothelial Function in Patients with Hypertension and Coronary Heart Disease. Chinese Journal of Evidence-Based Cardiovascular Medicine, 13(4): 438–442.
Yu LL, Lian W, Yu XY, et al., 2021, Clinical Study of Amlodipine Combined with Atorvastatin Calcium in the Treatment of Patients with Hypertension and Coronary Heart Disease. Chinese Journal of Clinical Pharmacology, 37(20): 2734–2737.
Zhou W, Li XQ, 2022, Analysis of the Standardized Treatment Effect of Amlodipine Combined with Atorvastatin Calcium Tablets on Hypertension Combined with Coronary Heart Disease. China Standardization, 2022(18): 270–272.
Disease M, 2023, The Efficacy of Rosuvastatin, Amlodipine, and Aspirin in the Treatment of Hypertension with Coronary Heart Disease and Its Effect on Platelet Aggregation. Disease Markers, 20(19): 1191–1994.
Zhang WQ, Liu B, 2022, Clinical Observation of Amlodipine Atorvastatin Calcium Tablets in the Treatment of Hypertension, Coronary Heart Disease with Carotid Atherosclerosis. Chinese Journal of Practical Medicine, 17(25): 125–127. https://doi.org/10.14163/j.cnki.11-5547/r.2022.25.035
Fu JL, Wang T, Li BT, et al., 2022, The Efficacy of Rosuvastatin, Amlodipine, and Aspirin in the Treatment of Hypertension with Coronary Heart Disease and Its Effect on Platelet Aggregation. Disease Markers, 2(5): 39–42.
Deng YJ, Song J, 2022, Effects of Amlodipine Combined with Atorvastatin on Cardiac Function and Immune Function in Patients with Hypertension and Coronary Heart Disease. Reflexotherapy & Rehabilitation Medicine, 3(19): 145–148.
Yu P, 2022, Study on the Efficacy and Safety of Amlodipine + Atorvastatin Calcium Tablets in the Treatment of Hypertension Combined with Coronary Heart Disease. Marriage, Fertility & Health, 28(3): 195–196.
Hideaki N, Hiroyuki S, Ikuo S, et al., 2021, Prevention of Acute Myocardial Infarction and Stroke with Amlodipine/Atorvastatin Single-Pill Therapy for Patients with Hypertension and Dyslipidemia. Journal of Hypertension, 39(11): 1377–1380.
Dezsi AC, 2018, Treatment with Triple Combination of Atorvastatin, Perindopril, and Amlodipine in Patients with Stable Coronary Artery Disease: A Subgroup Analysis from the PAPA-CAD Study. Journal of International Medical Research, 46(5): 1902–1909.
Galeeva ZM, Galiavich AS, 2014, A Fixed-dose Lisinopril and Amlodipine Combination in Conjunction with Rosuvastatin in Patients with Hypertensive Disease and Coronary Heart Disease. Terapevticheskii Arkhiv, 86(9): 71–76.
Huang CF, 2025, Study on the Effect of Amlodipine and Atorvastatin Calcium Tablets in the Treatment of Hypertension Complicated with Coronary Heart Disease and its Influence on Blood Pressure and Heart Function. Chinese Journal of Modern Drug Application, 19(11): 105–108.
Lu XY, 2024, Analysis of the Effect of Amlodipine Combined with Atorvastatin Calcium Tablets in the Treatment of Hypertension Complicated with Coronary Heart Disease. Chinese Journal of Practical Medicine, 51(22): 95–98.
Kengo A, Kazushi U, Kouichi T, et al., 2019, Effects of Single Pill-based Combination Therapy of Amlodipine and Atorvastatin on within-visit Blood Pressure Variability and Parameters of Renal and Vascular Function in Hypertensive Patients with Chronic Kidney Disease. BioMed Research International, 15(8): 456–458.
Liu B, 2023, Analysis of the Efficacy and Adverse Reactions of Amlodipine Combined with Atorvastatin Calcium Tablets in the Treatment of Hypertension Complicated with Coronary Heart Disease. Chinese Journal of Practical Therapeutics, 18(12): 108–110.
Leng DF, 2022, Clinical Efficacy Analysis of Amlodipine Combined with Atorvastatin Calcium Tablets in the Treatment of Hypertension Complicated with Coronary Heart Disease. Chinese Journal of Modern Drug Application, 16(11): 94–97.